Surveillance of the tumor mutanome by T cells during progression from primary

Surveillance of the tumor mutanome by T cells during progression from primary to 1 recurrent ovarian cancer 2 3 Authors 4 5 Darin A. Wick, 6 John R. Webb, 7 Julie S. Nielsen, 8 Spencer D. Martin, 9 David R. Kroeger, 10 Katy Milne, 11 Mauro Castellarin, 12 Kwame Twumasi-Boateng, 13 Peter H. Watson, 14 Rob A. Holt, 15 Brad H. Nelson, 16 17 Trev and Joyce Deeley Research Centre, British Columbia Cancer Agency, Victoria, British 18 Columbia, Canada, 19 Department of Biochemistry and Microbiology, University of Victoria, Victoria, British 20 Columbia, Canada, 21 Michael Smith Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, British 22 Columbia, Canada. 23 Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia, 24 Canada. 25 Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, British 26 Columbia, Canada. 27 Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, 28 British Columbia, Canada, 29 * Address correspondence to Dr. Brad H. Nelson, Trev and Joyce Deeley Research Centre, 30 British Columbia Cancer Agency, Victoria, BC, Canada, V8R 6V5. (Tel) 250-519-5705, (FAX) 31 250-519-2040, (email) [email protected] 32 33 Disclosure of Potential Conflicts of Interest: 34 35 The authors have no potential conflicts of interest to disclose. 36